Two major arterial roads, Routes U.S. 50 and Route 7, bisect the County east and west.  Route 340 bisects the County north and south.  Interstate 81 is approximately 8 miles west of Berryville and Route 66 is approximately 15 miles from Berryville close to Clarke County’s southern border.


The Norfolk -Southern’s “Crescent Corridor” rail line parallels Route 340 and passes through both Berryville and Boyce, as well as the Clarke County Business Park.  The “Crescent Corridor” provides rail service between New Orleans and New Jersey.  The segment of rail passing through Clarke County is designated as a high capacity route.

Virginia Inland Port

The Virginia Inland Port is located only a few miles from  Clarke County’s southern border in Warren County where the Inland Port is located.  The Virginia Inland Port is owned and operated by the Virginia Port Authority and is designed to provide quick and efficient delivery of container goods from the Shenandoalh Valley to Hampton Roads, one of the largest ports on the east coast, via the Norfolk Southern Railway.